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Issue 73, 2012
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Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

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Abstract

We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in a monolithic format. Sequential operations of separation, compartmentalisation and concentration counter were conducted on a monolithic chip. This describes the use of droplet-based microfluidics for the preservation of chromatographic separations, and its potential application as a high frequency fraction collector.

Graphical abstract: Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

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Article information


Submitted
25 May 2012
Accepted
23 Jul 2012
First published
24 Jul 2012

Chem. Commun., 2012,48, 9144-9146
Article type
Communication

Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation

J. Kim, S. Cho, D. Kang, J. B. Edel, S. Chang, A. J. deMello and D. O'Hare, Chem. Commun., 2012, 48, 9144
DOI: 10.1039/C2CC33774F

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