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Issue 61, 2012
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Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone–boronic acid hybrids

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Abstract

Target-selective photodegradation of 3-deoxy-D-manno-2-octulopyranosonic acid (KDO) was achieved without additives and under neutral conditions using a designed anthraquinoneboronic acid hybrid and long wavelength UV light irradiation. The hybrid can photodegrade lipopolysaccharides (LPS) and inhibit macrophage activation induced by LPS.

Graphical abstract: Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone–boronic acid hybrids

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Supplementary files

Article information


Submitted
17 May 2012
Accepted
07 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 7595-7597
Article type
Communication

Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinoneboronic acid hybrids

D. Takahashi, T. Miura and K. Toshima, Chem. Commun., 2012, 48, 7595
DOI: 10.1039/C2CC33559J

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