Jump to main content
Jump to site search

Issue 67, 2012
Previous Article Next Article

Surface-modified protein nanospheres as potential antiviral agents

Author affiliations

Abstract

A novel application of surface-modified protein nanospheres as potential antiviral agents is illustrated. By using a single-step sonochemical process, bovine serum albumin nanospheres were generated, whose surface was covalently conjugated with mercaptoethane sulfonate to chemically and electrostatically mimic cellular heparan sulfate. The nanospheres effectively inhibited HSV-1 infection.

Graphical abstract: Surface-modified protein nanospheres as potential antiviral agents

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 May 2012, accepted on 27 Jun 2012 and first published on 27 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33448H
Chem. Commun., 2012,48, 8359-8361

  •   Request permissions

    Surface-modified protein nanospheres as potential antiviral agents

    D. Baram-Pinto, S. Shukla, M. Richman, A. Gedanken, S. Rahimipour and R. Sarid, Chem. Commun., 2012, 48, 8359
    DOI: 10.1039/C2CC33448H

Search articles by author

Spotlight

Advertisements