Issue 60, 2012
From the journal:

Chemical Communications

Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides†

Bo Shen,a   Matthew W. Bedore,a   Adam Sniadya  and  Timothy F. Jamison*a  

* Corresponding authors

a Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, USA
E-mail: tfj@mit.edu
Fax: (+)1 617-324-0253

Abstract

A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly increased the efficiency and selectivity of the reaction.

Graphical abstract: Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC33356B
Article type
Communication
Submitted
09 May 2012
Accepted
06 Jun 2012
First published
22 Jun 2012

Chem. Commun., 2012,48, 7444-7446

Permissions

Request permissions

Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides

B. Shen, M. W. Bedore, A. Sniady and T. F. Jamison, Chem. Commun., 2012, 48, 7444 DOI: 10.1039/C2CC33356B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements