Issue 82, 2012
From the journal:

Chemical Communications

A bioresponsive controlled-release biosensor using Au nanocages capped with an aptamer-based molecular gate and its application in living cells†

Wei Wang,*a   Tao Yan,a   Shibin Cuia  and  Jun Wana  

* Corresponding authors

a State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China
E-mail: wangwei9612@126.com
Fax: +86 532 84022750
Tel: +86 532 84022750

Abstract

A novel bioresponsive controlled-release biosensor using Au nanocages capped with an aptamer-based molecular gate was reported for the first time. The use of aptamers as caps has proven to be a suitable method for the preparation of “bio-gated” delivery systems that can be selectively opened in the presence of target biomolecules.

Graphical abstract: A bioresponsive controlled-release biosensor using Au nanocages capped with an aptamer-based molecular gate and its application in living cells

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Article information

DOI
https://doi.org/10.1039/C2CC33165A
Article type
Communication
Submitted
02 May 2012
Accepted
30 Aug 2012
First published
31 Aug 2012

Chem. Commun., 2012,48, 10228-10230

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A bioresponsive controlled-release biosensor using Au nanocages capped with an aptamer-based molecular gate and its application in living cells

W. Wang, T. Yan, S. Cui and J. Wan, Chem. Commun., 2012, 48, 10228 DOI: 10.1039/C2CC33165A

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