Issue 60, 2012
From the journal:

Chemical Communications

Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays†

Yong Huang,ab   Shulin Zhao,*a   Zhen-Feng Chen,a   Ming Shia  and  Hong Liang*a  

* Corresponding authors

a Ministry of Education Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin, China
E-mail: zhaoshulin001@163.com, hliang@gxnu.edu.cn
Fax: +86 773 5832294
Tel: +86 773 5856104

b College of Chemistry and Chemical Engineering, Central South University, Changsha, China

Abstract

We have developed an amplified fluorescence polarization aptasensor that relies on aptamer structure-switching-triggered nanoparticles (NPs) enhancement for biomolecules detection. This new type of assay exhibits higher detection sensitivity over traditional homogeneous aptasensors by two orders of magnitude and high specificity for target molecules.

Graphical abstract: Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC33021K
Article type
Communication
Submitted
27 Apr 2012
Accepted
24 May 2012
First published
24 May 2012

Chem. Commun., 2012,48, 7480-7482

Permissions

Request permissions

Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays

Y. Huang, S. Zhao, Z. Chen, M. Shi and H. Liang, Chem. Commun., 2012, 48, 7480 DOI: 10.1039/C2CC33021K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements