Issue 66, 2012

Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

Abstract

G-quadruplex conformations within a sequence of three quadruplex units of human telomeric DNA were studied by two-frequency pulsed electron paramagnetic resonance (EPR) spectroscopy. In contrast to some individual G-quadruplexes, within the higher-order human telomeric sequence a (3+1) hybrid structure is formed.

Graphical abstract: Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

Supplementary files

Article information

Article type
Communication
Submitted
19 Mar 2012
Accepted
10 Apr 2012
First published
10 Apr 2012

Chem. Commun., 2012,48, 8258-8260

Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

V. Singh, M. Azarkh, M. Drescher and J. S. Hartig, Chem. Commun., 2012, 48, 8258 DOI: 10.1039/C2CC32012F

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