Jump to main content
Jump to site search

Issue 39, 2012
Previous Article Next Article

Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations

Author affiliations

Abstract

A novel methodology is presented for evaluating a dynamic ensemble of oligosaccharide conformations by lanthanide-assisted NMR spectroscopy combined with molecular dynamics (MD) simulations. The results obtained using the GM3 trisaccharide demonstrated that pseudocontact shift measurements offer a valuable experimental tool for the validation of MD simulations of highly flexible biomolecules.

Graphical abstract: Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations

Back to tab navigation

Supplementary files

Article information


Submitted
16 Jan 2012
Accepted
19 Mar 2012
First published
20 Mar 2012

Chem. Commun., 2012,48, 4752-4754
Article type
Communication

Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations

S. Yamamoto, Y. Zhang, T. Yamaguchi, T. Kameda and K. Kato, Chem. Commun., 2012, 48, 4752
DOI: 10.1039/C2CC30353A

Social activity

Search articles by author

Spotlight

Advertisements