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Issue 22, 2012
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A “one-pot” multicomponent approach to polysubstituted 4-aminopyridines

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Abstract

A novel and facile domino reaction has been developed to synthesize a variety of polysubstituted 4-aminopyridines from α-azidovinylketones, aldehydes and methylamine derivatives in reasonably good yields under mild conditions. Additionally, a possible mechanism is proposed.

Graphical abstract: A “one-pot” multicomponent approach to polysubstituted 4-aminopyridines

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Publication details

The article was received on 15 Dec 2011, accepted on 27 Jan 2012 and first published on 30 Jan 2012


Article type: Communication
DOI: 10.1039/C2CC17850H
Citation: Chem. Commun., 2012,48, 2785-2787

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    A “one-pot” multicomponent approach to polysubstituted 4-aminopyridines

    J. Shao, W. Yu, Z. Shao and Y. Yu, Chem. Commun., 2012, 48, 2785
    DOI: 10.1039/C2CC17850H

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