Issue 20, 2012
From the journal:

Chemical Communications

Nuclease cleavage-assisted target recycling for signal amplification of free-label impedimetric aptasensors†

Juan Tang,a   Dianping Tang,*a   Jun Zhou,a   Huanghao Yanga  and  Guonan Chen*a  

* Corresponding authors

a Key Laboratory of Analysis and Detection of Food Safety (Ministry of Education & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, P.R. China
E-mail: dianping.tang@fzu.edu.cn, gnchen@fzu.edu.cn
Fax: +86 591 22866135
Tel: +86 591 22866125

Abstract

A simple, novel, label-free impedimetric aptasensor with signal amplification is developed for ultrasensitive detection of small molecules on a carbon nanotubes-based sensing platform by combining target-induced release of the aptamers and nuclease cleavage-assisted target recycling.

Graphical abstract: Nuclease cleavage-assisted target recycling for signal amplification of free-label impedimetric aptasensors

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Article information

DOI
https://doi.org/10.1039/C2CC17536C
Article type
Communication
Submitted
02 Dec 2011
Accepted
12 Jan 2012
First published
16 Jan 2012

Chem. Commun., 2012,48, 2627-2629

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Nuclease cleavage-assisted target recycling for signal amplification of free-label impedimetric aptasensors

J. Tang, D. Tang, J. Zhou, H. Yang and G. Chen, Chem. Commun., 2012, 48, 2627 DOI: 10.1039/C2CC17536C

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