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Issue 39, 2012
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Synthesis and characterization of ratiometric nanosensors for pH quantification: a mixed micelle approach

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Abstract

Optical nanoparticle pH sensors designed for ratiometric measurements have previously been synthesized using post-functionalization approaches to introduce sensor molecules and to modify nanoparticle surface chemistry. This strategy often results in low control of the nanoparticle surface chemistry and is prone to batch-to-batch variations, which is undesirable for succeeding sensor calibrations and cellular measurements. Here we provide a new synthetic approach for preparing nanoparticle pH sensors based on self-organization principles, which in comparison to earlier strategies offers a much higher design flexibility and high control of particle size, morphology and surface chemistry.

Graphical abstract: Synthesis and characterization of ratiometric nanosensors for pH quantification: a mixed micelle approach

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Article information


Submitted
20 Nov 2011
Accepted
13 Mar 2012
First published
14 Mar 2012

Chem. Commun., 2012,48, 4776-4778
Article type
Communication

Synthesis and characterization of ratiometric nanosensors for pH quantification: a mixed micelle approach

E. K. Pramod Kumar, K. Almdal and T. L. Andresen, Chem. Commun., 2012, 48, 4776
DOI: 10.1039/C2CC17213E

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