Issue 8, 2012

Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

Abstract

Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.

Graphical abstract: Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

Supplementary files

Article information

Article type
Communication
Submitted
18 Oct 2011
Accepted
23 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 1129-1131

Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

C. Redshaw, M. R. J. Elsegood, J. A. Wright, H. Baillie-Johnson, T. Yamato, S. D. Giovanni and A. Mueller, Chem. Commun., 2012, 48, 1129 DOI: 10.1039/C2CC16480A

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