Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 2, 2012
Previous Article Next Article

Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides

Author affiliations

Abstract

A protocol for the Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides that minimizes protodeboronation is described. A combination of catalytic amounts of Pd(OAc)2 and SPhos in conjunction with CsF in isopropanol effectively affords a variety of coupled products. Surprisingly, a dramatic temperature dependence in product selectivity was observed.

Graphical abstract: Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Sep 2011, accepted on 28 Oct 2011 and first published on 14 Nov 2011


Article type: Communication
DOI: 10.1039/C1CC15990A
Citation: Chem. Commun., 2012,48, 203-205

  •   Request permissions

    Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides

    A. Thakur, K. Zhang and J. Louie, Chem. Commun., 2012, 48, 203
    DOI: 10.1039/C1CC15990A

Search articles by author

Spotlight

Advertisements