Issue 5, 2012
From the journal:

Chemical Communications

Wavelength-orthogonal photolysis of neurotransmittersin vitro†

Megan N. Stanton-Humphreys,‡ab   Ruth D. T. Taylor,‡b   Craig McDougall,c   Mike L. Hart,b   C. Tom A. Brown,c   Nigel J. Emptage*b  and  Stuart J. Conway*a  

* Corresponding authors

a Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, UK
E-mail: stuart.conway@chem.ox.ac.uk
Fax: + 44 (0)1865 285002
Tel: +44 (0)1865 285109

b Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, UK
E-mail: nigel.emptage@pharm.ox.ac.uk
Fax: + 44 (0)1865 271853
Tel: + 44 (0)1865 271588

c School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife, UK.

Abstract

Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged γ-amino butyric acid (GABA) on neurons, at ∼260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.

Graphical abstract: Wavelength-orthogonal photolysis of neurotransmittersin vitro

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Article information

DOI
https://doi.org/10.1039/C1CC15135E
Article type
Communication
Submitted
18 Aug 2011
Accepted
21 Sep 2011
First published
07 Oct 2011

Chem. Commun., 2012,48, 657-659

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Wavelength-orthogonal photolysis of neurotransmittersin vitro

M. N. Stanton-Humphreys, R. D. T. Taylor, C. McDougall, M. L. Hart, C. T. A. Brown, N. J. Emptage and S. J. Conway, Chem. Commun., 2012, 48, 657 DOI: 10.1039/C1CC15135E

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