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Issue 41, 2011
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Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the ‘click’ labelling of biomolecules

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Abstract

A convenient synthesis of azidomethyl-ruthenocene and its use in the covalent labelling of amino acids, peptides and a peptide nucleic acid (PNA) monomer derivative by Cu(I) catalyzed azide–alkyne coupling (Cu-AAC, “click chemistry”) are described.

Graphical abstract: Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the ‘click’ labelling of biomolecules

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Publication details

The article was received on 25 Jul 2011, accepted on 12 Sep 2011 and first published on 21 Sep 2011


Article type: Communication
DOI: 10.1039/C1CC14537A
Chem. Commun., 2011,47, 11444-11446

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    Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the ‘click’ labelling of biomolecules

    M. Patra and N. Metzler-Nolte, Chem. Commun., 2011, 47, 11444
    DOI: 10.1039/C1CC14537A

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