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Issue 39, 2011
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Fluorescence detection of coralyne and polyadenylation reaction using an oligonucleotide-based fluorogenic probe

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Abstract

This study describes the development of a simple, sensitive, and selective-detection system for coralyne and polyadenylation reaction based on the fact that coralyne induces a conformational change of the polyadenosine [poly(A)] oligonucleotide through A–coralyne–A coordination, thereby enhancing the fluorescence of SYBR Green I.

Graphical abstract: Fluorescence detection of coralyne and polyadenylation reaction using an oligonucleotide-based fluorogenic probe

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Publication details

The article was received on 21 Jul 2011, accepted on 22 Aug 2011 and first published on 07 Sep 2011


Article type: Communication
DOI: 10.1039/C1CC14429D
Chem. Commun., 2011,47, 11134-11136

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    Fluorescence detection of coralyne and polyadenylation reaction using an oligonucleotide-based fluorogenic probe

    Y. Lin and W. Tseng, Chem. Commun., 2011, 47, 11134
    DOI: 10.1039/C1CC14429D

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