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Issue 37, 2011
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Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones

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Abstract

A one-pot Yb(III)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e.quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α.

Graphical abstract: Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones

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Publication details

The article was received on 21 Jun 2011, accepted on 01 Aug 2011 and first published on 19 Aug 2011


Article type: Communication
DOI: 10.1039/C1CC13695J
Chem. Commun., 2011,47, 10263-10265

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    Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones

    K. S. Kumar, P. M. Kumar, M. A. Reddy, Md. Ferozuddin, M. Sreenivasulu, A. A. Jafar, G. R. Krishna, C. M. Reddy, D. Rambabu, K. Shiva Kumar, S. Pal and M. Pal, Chem. Commun., 2011, 47, 10263
    DOI: 10.1039/C1CC13695J

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