Issue 28, 2011
From the journal:

Chemical Communications

DNA-templated ensemble for label-free and real-time fluorescence turn-on detection of enzymatic/oxidative cleavage of single-stranded DNA†

Xinjian Yang,ab   Fang Pu,a   Jinsong Ren*a  and  Xiaogang Qua  

* Corresponding authors

a State Key Laboratory of Rare Earth Resources Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: jren@ciac.jl.cn

b Graduate School of the Chinese Academy of Sciences, Beijing, China

Abstract

We have demonstrated a DNA-templated small molecule ensemble that allows the label-free fluorescence turn-on detection of enzymatic or oxidative cleavage of single-stranded DNA with high sensitivity and selectivity.

Graphical abstract: DNA-templated ensemble for label-free and real-time fluorescence turn-on detection of enzymatic/oxidative cleavage of single-stranded DNA

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Article information

DOI
https://doi.org/10.1039/C1CC12216A
Article type
Communication
Submitted
18 Apr 2011
Accepted
09 May 2011
First published
31 May 2011

Chem. Commun., 2011,47, 8133-8135

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DNA-templated ensemble for label-free and real-time fluorescence turn-on detection of enzymatic/oxidative cleavage of single-stranded DNA

X. Yang, F. Pu, J. Ren and X. Qu, Chem. Commun., 2011, 47, 8133 DOI: 10.1039/C1CC12216A

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