Issue 26, 2011
From the journal:

Chemical Communications

Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis†

Yugang Huang,a   Yonghong Zeng,a   Jianwen Yang,*ab   Zhaohua Zeng,ab   Fangming Zhu*ab  and  Xudong Chenab  

* Corresponding authors

a Institute of Polymer Science, DSAPM Lab, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, GuangZhou, China
E-mail: cesyjw@mail.sysu.edu.cn
Tel: +86-20-8411-1138

b Key Lab for Polymer Composite and Functional Materials of Ministry of Education, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, GuangZhou, China
E-mail: ceszfm@mail.sysu.edu.cn

Abstract

Rapid and highly efficient side-chain functionalization of polypeptides was achieved via combination of ring-opening polymerization of a new clickable monomer of γ-propargyl-L-glutamateN-carboxyanhydride (PLG-NCA) and thiol-yne photochemistry, which provides a convenient and universal route to prepare diverse polypeptide-based biomimetic hybrid materials.

Graphical abstract: Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis

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Article information

DOI
https://doi.org/10.1039/C1CC12177D
Article type
Communication
Submitted
15 Apr 2011
Accepted
16 May 2011
First published
31 May 2011

Chem. Commun., 2011,47, 7509-7511

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Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis

Y. Huang, Y. Zeng, J. Yang, Z. Zeng, F. Zhu and X. Chen, Chem. Commun., 2011, 47, 7509 DOI: 10.1039/C1CC12177D

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