Issue 26, 2011
From the journal:

Chemical Communications

Pb2+-introduced activation of horseradish peroxidase (HRP)-mimicking DNAzyme†

Xi Zhu,a   Xiaoyao Gao,a   Qida Liu,b   Zhenyu Lin,*a   Bin Qiua  and  Guonan Chen*a  

* Corresponding authors

a Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian, China
E-mail: zylin@fzu.edu.cn, gnchen@fzu.edu.cn
Fax: (+86)-591-22866135

b MOE Key Laboratory for Strength and Vibration, Xi'an Jiaotong University, China

Abstract

A novel nucleic acid hairpin structure composed of Pb2+-dependent DNAzyme and HRP-mimicking DNAzyme was developed. This hairpin structure can be used as a sensor for the detection of Pb2+ based on colorimetry.

Graphical abstract: Pb2+-introduced activation of horseradish peroxidase (HRP)-mimicking DNAzyme

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Article information

DOI
https://doi.org/10.1039/C1CC11349F
Article type
Communication
Submitted
08 Mar 2011
Accepted
24 Mar 2011
First published
17 May 2011

Chem. Commun., 2011,47, 7437-7439

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Pb2+-introduced activation of horseradish peroxidase (HRP)-mimicking DNAzyme

X. Zhu, X. Gao, Q. Liu, Z. Lin, B. Qiu and G. Chen, Chem. Commun., 2011, 47, 7437 DOI: 10.1039/C1CC11349F

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