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Issue 19, 2011
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Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug

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Abstract

Self-assembly supramolecular nanoparticles (SNPs) are synthesized using polyethylenimine (PEI) crosslinked by cyclodextrins (CyDs), adamantyl doxorubicin and plasmidDNA. SNPs successfully conduct the cooperative co-delivery of chemotherapeutic anticancer drug and plasmidDNAin vitro and in vivo.

Graphical abstract: Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug

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Article information


Submitted
07 Feb 2011
Accepted
21 Mar 2011
First published
06 Apr 2011

Chem. Commun., 2011,47, 5572-5574
Article type
Communication

Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug

Q. Hu, H. Fan, Y. Ping, W. Liang, G. Tang and J. Li, Chem. Commun., 2011, 47, 5572
DOI: 10.1039/C1CC10721F

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