Issue 17, 2011
From the journal:

Chemical Communications

Inhibition of Acinetobacter baumanniibiofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit†

Lingling Peng,‡a   Joseph DeSousa,‡a   Zhaoming Su,a   Bruce M. Novak,a   Alexander A. Nevzorov,a   Eva R. Garlandb  and  Christian Melander*a  

* Corresponding authors

a North Carolina State University, Department of Chemistry, Raleigh, North Carolina, USA
E-mail: Christian_Melander@ncsu.edu

b Agile Sciences, 1791 Varsity Drive, Suite 150, Raleigh, North Carolina, USA

Abstract

A polymeric composite containing a 2-aminoimidazole derivative was synthesized. It was found that this polymer was resistant to biofilm colonization by Acinetobacter baumannii, no leaching of the 2-aminoimidazole derivative was observed after 2 weeks of treatment with deionized water, and the resulting polymer was not hemolytic.

Graphical abstract: Inhibition of Acinetobacter baumanniibiofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit

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Article information

DOI
https://doi.org/10.1039/C1CC10691K
Article type
Communication
Submitted
04 Feb 2011
Accepted
10 Mar 2011
First published
25 Mar 2011

Chem. Commun., 2011,47, 4896-4898

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Inhibition of Acinetobacter baumanniibiofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit

L. Peng, J. DeSousa, Z. Su, B. M. Novak, A. A. Nevzorov, E. R. Garland and C. Melander, Chem. Commun., 2011, 47, 4896 DOI: 10.1039/C1CC10691K

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