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Issue 17, 2011
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Quantitative detection of adenosine in urine using silver enhancement of aptamer–gold nanoparticle aggregation and progressive dilution

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Abstract

We implement the progressive dilution strategy to bring assays based on gold nanoparticles to a quantitative level. This is demonstrated by the detection of adenosine in urine by combining progressive dilution with the silver enhancement of aptamer–gold nanoparticle aggregation, giving good accuracy, high selectivity, and an unlimited dynamic range above LOD.

Graphical abstract: Quantitative detection of adenosine in urine using silver enhancement of aptamer–gold nanoparticle aggregation and progressive dilution

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Publication details

The article was received on 24 Jan 2011, accepted on 17 Mar 2011 and first published on 28 Mar 2011


Article type: Communication
DOI: 10.1039/C1CC10460H
Citation: Chem. Commun., 2011,47, 4956-4958
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    Quantitative detection of adenosine in urine using silver enhancement of aptamer–gold nanoparticle aggregation and progressive dilution

    Z. F. Liu, J. Ge and X. S. Zhao, Chem. Commun., 2011, 47, 4956
    DOI: 10.1039/C1CC10460H

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