Issue 15, 2011

Controllable exploding microcapsules as drug carriers

Abstract

Controllable exploding polyelectrolyte microcapsules were developed by layer-by-layer assembly of poly(allylamine hydrochloride) (PAH) and poly(sodium 4-styrenesulfonate) (PSS) on a dextran microgel core containing a cleavable disulfide bond fabricated via click chemistry. The microcapsules can explode upon the injection of DTT with an explosive release of the drug.

Graphical abstract: Controllable exploding microcapsules as drug carriers

Supplementary files

Article information

Article type
Communication
Submitted
18 Jan 2011
Accepted
22 Feb 2011
First published
09 Mar 2011

Chem. Commun., 2011,47, 4457-4459

Controllable exploding microcapsules as drug carriers

J. Zhang, C. Li, Y. Wang, R. Zhuo and X. Zhang, Chem. Commun., 2011, 47, 4457 DOI: 10.1039/C1CC10337G

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