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Issue 17, 2011
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Reactive oxygen species in photochemistry of the red fluorescent protein “Killer Red”

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Abstract

The fluorescent protein aptly named “Killer Red” (KRed) is capable of killing transfected cells and inactivating fused proteins upon exposure to visible light in the presence of oxygen. We have investigated the source of the bioactive species through a variety of photophysical and photochemical techniques. Our results indicate a Type I (electron transfer mediated) photosensitizing mechanism.

Graphical abstract: Reactive oxygen species in photochemistry of the red fluorescent protein “Killer Red”

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Supplementary files

Article information


Submitted
21 Dec 2010
Accepted
09 Feb 2011
First published
28 Feb 2011

Chem. Commun., 2011,47, 4887-4889
Article type
Communication

Reactive oxygen species in photochemistry of the red fluorescent protein “Killer Red”

R. B. Vegh, K. M. Solntsev, M. K. Kuimova, S. Cho, Y. Liang, B. L. W. Loo, L. M. Tolbert and A. S. Bommarius, Chem. Commun., 2011, 47, 4887
DOI: 10.1039/C0CC05713D

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