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Issue 7, 2011
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Osmium(vi) complexes as a new class of potential anti-cancer agents

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Abstract

A nitridoosmium(VI) complex [OsVI(N)(sap)(OH2)Cl] (H2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate.

Graphical abstract: Osmium(vi) complexes as a new class of potential anti-cancer agents

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Supplementary files

Article information


Submitted
20 Oct 2010
Accepted
06 Dec 2010
First published
04 Jan 2011

Chem. Commun., 2011,47, 2140-2142
Article type
Communication

Osmium(VI) complexes as a new class of potential anti-cancer agents

W. Ni, W. Man, M. T. Cheung, R. W. Sun, Y. Shu, Y. Lam, C. Che and T. Lau, Chem. Commun., 2011, 47, 2140
DOI: 10.1039/C0CC04515B

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