Issue 6, 2011
From the journal:

Chemical Communications

Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release†

Shang-Hsiu Hu,a   You-Yin Chen,b   Ta-Chung Liu,a   Tsan-Hua Tung,a   Dean-Mo Liu*a  and  San-Yuan Chen*a  

* Corresponding authors

a Department of Materials Sciences and Engineering, National Chiao Tung University, Hsinchu, Taiwan
E-mail: sanyuanchen@mail.nctu.edu.tw, deanmo_liu@yahoo.ca

b Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan

Abstract

Yolk/shell capsules containing a volume/hydrophobicity transformable core and an ultra-thin silica shell have been prepared. When an external magnetic field induced the temperature, the cores exhibit a significant triggering size shrinkage and the diameter decreases more than 10 times, causing solid shells destruction and physical collapse, leading to drug burst release.

Graphical abstract: Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

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Article information

DOI
https://doi.org/10.1039/C0CC03998E
Article type
Communication
Submitted
21 Sep 2010
Accepted
16 Nov 2010
First published
02 Dec 2010

Chem. Commun., 2011,47, 1776-1778

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Remotely nano-rupturable yolk/shell capsules for magnetically-triggered drug release

S. Hu, Y. Chen, T. Liu, T. Tung, D. Liu and S. Chen, Chem. Commun., 2011, 47, 1776 DOI: 10.1039/C0CC03998E

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