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Issue 3, 2011
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A general and mild domino approach to substituted 1-aminoindoles

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Abstract

A versatile and efficient palladium catalyzed domino reaction leading to a broad range of substituted 1-aminoindoles has been developed. The title compounds were prepared from 2-halo-phenylacetylenes and simple hydrazines in good to excellent yields in just a few hours under mild conditions.

Graphical abstract: A general and mild domino approach to substituted 1-aminoindoles

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Publication details

The article was received on 31 Aug 2010, accepted on 25 Oct 2010 and first published on 12 Nov 2010


Article type: Communication
DOI: 10.1039/C0CC03584J
Citation: Chem. Commun., 2011,47, 1042-1044

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    A general and mild domino approach to substituted 1-aminoindoles

    N. Halland, M. Nazaré, J. Alonso, O. R'kyek and A. Lindenschmidt, Chem. Commun., 2011, 47, 1042
    DOI: 10.1039/C0CC03584J

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