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Issue 1, 2011
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Coarse-grained simulations of stretching entangled DNA using oscillating electric fields

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Abstract

DNA stretching in entangling media with oscillating electric fields is useful in DNA sequencing. We propose that stretching occurs around hairpin loops at the chain ends, caused by interactions with the medium. Brownian dynamics simulations show that this mechanism explains several experimental observations, including a resonance with varying field frequency.

Graphical abstract: Coarse-grained simulations of stretching entangled DNA using oscillating electric fields

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Publication details

The article was received on 25 Jun 2010, accepted on 06 Aug 2010 and first published on 08 Sep 2010


Article type: Communication
DOI: 10.1039/C0CC02090G
Citation: Chem. Commun., 2011,47, 337-339

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    Coarse-grained simulations of stretching entangled DNA using oscillating electric fields

    R. S. Graham and R. G. Larson, Chem. Commun., 2011, 47, 337
    DOI: 10.1039/C0CC02090G

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