Issue 1, 2011
From the journal:

Chemical Communications

Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions†‡

Carlo Cassani,§a   Xu Tian,§a   Eduardo C. Escudero-Adána  and  Paolo Melchiorre*ab  

* Corresponding authors

a ICIQ-Institute of Chemical Research of Catalonia, Av. Països Catalans 16, 43007 Tarragona, Spain
E-mail: pmelchiorre@iciq.es
Tel: +34 977920208

b ICREA-Institució Catalana de Recerca i Estudis Avançats, Pg. Lluís Companys 23, 08010 Barcelona, Spain

Abstract

Three distinct aminocatalytic cascade reactions leading to enantiomerically pure spirocyclic benzofuranones have been devised, highlighting the ability of organocascade to generate high degrees of stereochemical and architectural complexity in a single chemical transformation.

Graphical abstract: Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions

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Article information

DOI
https://doi.org/10.1039/C0CC01957G
Article type
Communication
Submitted
18 Jun 2010
Accepted
22 Jul 2010
First published
19 Aug 2010

Chem. Commun., 2011,47, 233-235

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Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions

C. Cassani, X. Tian, E. C. Escudero-Adán and P. Melchiorre, Chem. Commun., 2011, 47, 233 DOI: 10.1039/C0CC01957G

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