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Issue 47, 2010
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Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides†

Dongbing Zhao,a   Chao Gao,a   Xiaoyu Su,a   Yunqing He,a   Jingsong You*a  and  Ying Xue*a  
Author affiliations

* Corresponding authors

a Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, and State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, P.R. China
E-mail: jsyou@scu.edu.cn
Fax: (+86) 28-85412203

Abstract

The copper-catalyzed decarboxylative reactions of alkynyl carboxylic acids with aryl halides were performed under relatively mild reaction conditions. Benzofurans could be further prepared smoothly by a one-pot domino protocol on the basis of decarboxylative cross-coupling of 2-iodophenol.

Graphical abstract: Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides

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Publication details

The article was received on 10 Sep 2010, accepted on 11 Oct 2010 and first published on 04 Nov 2010


Article type: Communication
DOI: 10.1039/C0CC03772A
Chem. Commun., 2010,46, 9049-9051

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    Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides

    D. Zhao, C. Gao, X. Su, Y. He, J. You and Y. Xue, Chem. Commun., 2010, 46, 9049
    DOI: 10.1039/C0CC03772A

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