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Issue 42, 2010
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Efficient photoactivation of a Diels-Alderase ribozyme

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Abstract

Here we report the first example of a photoactivatable ribozyme which catalyzes a bimolecular reaction of two small organic molecules with multiple turnover, under control of a photo-cleavable protecting group by exploiting the structural significance of a single hydrogen bond.

Graphical abstract: Efficient photoactivation of a Diels-Alderase ribozyme

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Article information


Submitted
10 Aug 2010
Accepted
09 Sep 2010
First published
27 Sep 2010

Chem. Commun., 2010,46, 7975-7977
Article type
Communication

Efficient photoactivation of a Diels-Alderase ribozyme

A. Nierth, M. Singer and A. Jäschke, Chem. Commun., 2010, 46, 7975
DOI: 10.1039/C0CC03162C

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