Issue 38, 2010
From the journal:

Chemical Communications

Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch†

Xueqin An,*ab   Fan Zhang,b   Yinyan Zhub  and  Weiguo Shena  

* Corresponding authors

a School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, China
E-mail: anxueqin@ecust.edu.cn
Fax: 86-021-64252012
Tel: 86-021-64252012

b Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Environment Science, Nanjing Normal University, Nanjing, Jiangsu, China

Abstract

A thermosensitive liposome with embedded AuNPs in a bilayer was prepared using supercritical CO2. The AuNPs-liposome can absorb a certain wavelength light, convert optical energy into heat, induce phase transition, and release drug. The results show that drug release from the liposome is due to the photothermic effects inducing phase transition of the liposome rather than destruction of the liposome structure.

Graphical abstract: Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch

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Article information

DOI
https://doi.org/10.1039/C0CC03142A
Article type
Communication
Submitted
10 Aug 2010
Accepted
12 Aug 2010
First published
27 Aug 2010

Chem. Commun., 2010,46, 7202-7204

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Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch

X. An, F. Zhang, Y. Zhu and W. Shen, Chem. Commun., 2010, 46, 7202 DOI: 10.1039/C0CC03142A

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