Issue 37, 2010
From the journal:

Chemical Communications

Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2′-deoxyinosine†

Jing Zhang,ab   XiaoYan Wu,a   PingPing Chen,a   NingTing Lin,a   JingHua Chen,*a   GuoNan Chena  and  FengFu Fu*a  

* Corresponding authors

a Key Lab of Analysis and Detection for Food Safety of Ministry of Education, Department of Chemistry, Fuzhou University, Fujian 350108, China
E-mail: fengfu@fzu.edu.cn, cjh_huaxue@126.com
Fax: +86 59122866135
Tel: +86 59122866135

b Pharmaceutical Department, Fujian College of Medical Occupation and Technology, Fuzhou, Fujian 350101, China

Abstract

A novel electrochemical biosensor for the genotyping/detection of single-nucleotide polymorphisms (SNPs) of trace oral-cancer salivary DNA based on junction probes containing 2′-deoxyinosine (dI) residues is described.

Graphical abstract: Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2′-deoxyinosine

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Article information

DOI
https://doi.org/10.1039/C0CC02080J
Article type
Communication
Submitted
25 Jun 2010
Accepted
06 Aug 2010
First published
23 Aug 2010

Chem. Commun., 2010,46, 6986-6988

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Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2′-deoxyinosine

J. Zhang, X. Wu, P. Chen, N. Lin, J. Chen, G. Chen and F. Fu, Chem. Commun., 2010, 46, 6986 DOI: 10.1039/C0CC02080J

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