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Issue 36, 2010
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Construction of 3-oxyindoles via hypervalent iodine mediated tandem cyclization–acetoxylation of o-acyl anilines

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Abstract

An efficient tandem cyclization–acetoxylation of o-acyl anilines mediated by the combination of iodobenzene diacetate with tetrabutylammonium iodide provides a new convenient and useful route to 2-acetoxy indolin-3-ones, which are ready to be converted into other 2-substituted 3-oxyindole derivatives.

Graphical abstract: Construction of 3-oxyindoles via hypervalent iodine mediated tandem cyclization–acetoxylation of o-acyl anilines

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Article information


Submitted
16 Jun 2010
Accepted
06 Jul 2010
First published
23 Aug 2010

Chem. Commun., 2010,46, 6834-6836
Article type
Communication

Construction of 3-oxyindoles via hypervalent iodine mediated tandem cyclization–acetoxylation of o-acyl anilines

Y. Sun and R. Fan, Chem. Commun., 2010, 46, 6834
DOI: 10.1039/C0CC01911A

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