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Issue 33, 2010
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DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips

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Abstract

A DNA-bridged strategy is used to facilely conjugate streptavidin (STV) to luminescent semiconductor quantum dots (QDs), which leads to convenient and stable QD–DNAbiotin–STV conjugates that serve as fluorescent nanoprobes for ultrasensitive detection of cancer biomarkers with a microfluidic protein chip.

Graphical abstract: DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips

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Publication details

The article was received on 27 May 2010, accepted on 24 Jun 2010 and first published on 27 Jul 2010


Article type: Communication
DOI: 10.1039/C0CC01608J
Chem. Commun., 2010,46, 6126-6128

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    DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips

    M. Hu, Y. He, S. Song, J. Yan, H. Lu, L. Weng, L. Wang and C. Fan, Chem. Commun., 2010, 46, 6126
    DOI: 10.1039/C0CC01608J

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