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Issue 33, 2010
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DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips

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Abstract

A DNA-bridged strategy is used to facilely conjugate streptavidin (STV) to luminescent semiconductor quantum dots (QDs), which leads to convenient and stable QD–DNAbiotin–STV conjugates that serve as fluorescent nanoprobes for ultrasensitive detection of cancer biomarkers with a microfluidic protein chip.

Graphical abstract: DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips

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Article information


Submitted
27 May 2010
Accepted
24 Jun 2010
First published
27 Jul 2010

Chem. Commun., 2010,46, 6126-6128
Article type
Communication

DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips

M. Hu, Y. He, S. Song, J. Yan, H. Lu, L. Weng, L. Wang and C. Fan, Chem. Commun., 2010, 46, 6126
DOI: 10.1039/C0CC01608J

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