Issue 33, 2010
From the journal:

Chemical Communications

Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using rutheniumnanoparticle-based ultrasensitive chemiluminescence detection†

Sai Bi,a   Shuangyuan Hao,a   Li Lia  and  Shusheng Zhang*a  

* Corresponding authors

a Key Laboratory of Eco-chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
E-mail: shushzhang@126.com
Fax: +86 532 84022750
Tel: +86 532 84022750

Abstract

Bio-bar-code dendrimer-like DNA (bbc-DL-DNA) is employed as a label for the amplification assay of cancer cells in combination with the newly explored chemiluminescence (CL) system of luminol–H2O2–Ru3+ and specificity of structure-switching aptamers selected by cell-based SELEX.

Graphical abstract: Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection

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Article information

DOI
https://doi.org/10.1039/C0CC01409E
Article type
Communication
Submitted
14 May 2010
Accepted
25 Jun 2010
First published
23 Jul 2010

Chem. Commun., 2010,46, 6093-6095

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Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection

S. Bi, S. Hao, L. Li and S. Zhang, Chem. Commun., 2010, 46, 6093 DOI: 10.1039/C0CC01409E

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