Issue 35, 2010
From the journal:

Chemical Communications

Bioinspired fabrication of 3D hierarchical porous nanomicrostructures of calcium carbonate for bone regeneration†

Hai-Dong Yu,a   Zhi-Yong Zhang,b   Khin Yin Win,a   Jerry Chan,b   Swee Hin Teoh*b  and  Ming-Yong Han*ab  

* Corresponding authors

a Institute of Materials Research and Engineering, A-STAR, Singapore 117602
E-mail: my-han@imre.a-star.edu.sg
Tel: +65-68741987

b Division of Bioengineering, Department of Mechanical Engineering, and Department of Obstetrics and Gynecology, National University of Singapore, Singapore 117574
E-mail: biehanmy@nus.edu.sg, mpetsh@nus.edu.sg

Abstract

Hierarchical calcium carbonate structures with multi-scale organization have been successfully fabricated covering the full range of pore sizes from nano-, to micro- to macrofeatures. The resulting 3D scaffolds, with a close resemblance to bone structures, have been evaluated in vitro and in vivo and showed great potential for bone regeneration.

Graphical abstract: Bioinspired fabrication of 3D hierarchical porous nanomicrostructures of calcium carbonate for bone regeneration

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Article information

DOI
https://doi.org/10.1039/C0CC01348J
Article type
Communication
Submitted
11 May 2010
Accepted
28 Jul 2010
First published
16 Aug 2010

Chem. Commun., 2010,46, 6578-6580

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Bioinspired fabrication of 3D hierarchical porous nanomicrostructures of calcium carbonate for bone regeneration

H. Yu, Z. Zhang, K. Y. Win, J. Chan, S. H. Teoh and M. Han, Chem. Commun., 2010, 46, 6578 DOI: 10.1039/C0CC01348J

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