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Issue 18, 2010
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A pH-responsive fluorescence probe and photosensitiser based on a tetraamino silicon(iv) phthalocyanine

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Abstract

A novel tetraamino silicon(IV) phthalocyanine has been prepared, of which the fluorescence emission and reactive oxygen species generation efficiency are greatly enhanced at lower pH in the range of ca. 5–7, making it a promising pH-controlled and tumour-selective fluorescence probe and photosensitiser for photodynamic therapy.

Graphical abstract: A pH-responsive fluorescence probe and photosensitiser based on a tetraamino silicon(iv) phthalocyanine

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Supplementary files

Article information


Submitted
11 Jan 2010
Accepted
17 Feb 2010
First published
16 Mar 2010

Chem. Commun., 2010,46, 3188-3190
Article type
Communication

A pH-responsive fluorescence probe and photosensitiser based on a tetraamino silicon(IV) phthalocyanine

X. Jiang, P. Lo, S. Yeung, W. Fong and D. K. P. Ng, Chem. Commun., 2010, 46, 3188
DOI: 10.1039/C000605J

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