Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

Abstract

The first enantioselective total synthesis of (+)-stachyflin, a potential anti-influenza A virus agent, was achieved; the method features a BF₃·Et₂O-induced domino epoxide-opening/rearrangement/cyclization reaction to stereoselectively form the requisite pentacyclic ring system in one step.