Issue 17, 2010
From the journal:

Chemical Communications

Design, synthesis, and complementary recognition of β-hairpin peptides stabilized by artificial DNA base-pairing amino acids†

Katsuhiro Isozaki*a  and  Kazushi Mikiab  

* Corresponding authors

a Organic Nanomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
E-mail: ISOZAKI.Katsuhiro@nims.go.jp
Fax: +81-29-860-4718
Tel: +81-29-860-4718

b Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan

Abstract

A novel DNA base-pairing β-hairpin peptide involving intramolecular hydrogen bonds for induction of β-hairpin secondary structure and intermolecular complementary hydrogen bonds between thymine and diaminopyridine for molecular recognition has been synthesized.

Graphical abstract: Design, synthesis, and complementary recognition of β-hairpin peptides stabilized by artificial DNA base-pairing amino acids

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Article information

DOI
https://doi.org/10.1039/B924239B
Article type
Communication
Submitted
18 Nov 2009
Accepted
13 Feb 2010
First published
08 Mar 2010

Chem. Commun., 2010,46, 2947-2949

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Design, synthesis, and complementary recognition of β-hairpin peptides stabilized by artificial DNA base-pairing amino acids

K. Isozaki and K. Miki, Chem. Commun., 2010, 46, 2947 DOI: 10.1039/B924239B

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