Issue 41, 2009
From the journal:

Chemical Communications

Droplet-based compartmentalization of chemically separated components in two-dimensional separations†

X. Z. Niu,‡ab   B. Zhang,‡a   R. T. Marszalek,a   O. Ces,a   J. B. Edel,ab   D. R. Kluga  and  A. J. deMello*a  

* Corresponding authors

a Department of Chemistry, Imperial College London, South Kensington, London, UK
E-mail: a.demello@imperial.ac.uk
Fax: +44 207 594 5801
Tel: +44 207 594 5820

b Institute of Biomedical Engineering, Imperial College London, South Kensington, London, UK

Abstract

We demonstrate that nanolitre-sized droplets are an effective tool in coupling two-dimensional separations in both time and space. Using a microfluidic droplet connector, chemically separated components can be segmented into nanolitre droplets. After oil filtering and droplet merging, these droplets are loaded into a second dimension for comprehensive separations.

Graphical abstract: Droplet-based compartmentalization of chemically separated components in two-dimensional separations

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Article information

DOI
https://doi.org/10.1039/B918100H
Article type
Communication
Submitted
02 Sep 2009
Accepted
15 Sep 2009
First published
24 Sep 2009

Chem. Commun., 2009, 6159-6161

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Droplet-based compartmentalization of chemically separated components in two-dimensional separations

X. Z. Niu, B. Zhang, R. T. Marszalek, O. Ces, J. B. Edel, D. R. Klug and A. J. deMello, Chem. Commun., 2009, 6159 DOI: 10.1039/B918100H

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