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Issue 21, 2009
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Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

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Abstract

The copper(I)-catalyzed synthesis of a range of primary anilines from electron-rich and electron-deficient aryl halides including aryl chlorides has been achieved with aqueous ammonia, avoiding the need for inert atmosphere, expensive catalysts and ligands, anhydrous solvents, and additional base or other additives.

Graphical abstract: Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

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Publication details

The article was received on 02 Mar 2009, accepted on 14 Apr 2009 and first published on 27 Apr 2009


Article type: Communication
DOI: 10.1039/B904188E
Chem. Commun., 2009, 3035-3037

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    Efficient copper-catalyzed coupling of aryl chlorides, bromides and iodides with aqueous ammonia

    H. Xu and C. Wolf, Chem. Commun., 2009, 3035
    DOI: 10.1039/B904188E

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