TiO2-assisted silver enhanced biosensor for kinase activity profiling

Ji Ji; Hui Yang; Yun Liu; Hui Chen; Jilie Kong; Baohong Liu

doi:10.1039/B820738K

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TiO₂-assisted silver enhanced biosensor for kinase activity profiling†

Ji Ji,^a Hui Yang,^a Yun Liu,^a Hui Chen,^a Jilie Kong^a and Baohong Liu*^a

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* Corresponding authors

^a Department of Chemistry and Institute of Biomedical Sciences, Fudan University, Shanghai, P.R. China
E-mail: bhliu@fudan.edu.cn
Fax: +86 21 65641740
Tel: +86 21 65642405

Abstract

An electrochemical biosensor has been developed for sensitive determination of protein kinase activity and inhibition, taking advantage of specific binding of the phosphate groups with TiO₂nanoparticles, on which silver nanoparticles are photo-catalytically deposited to achieve signal enhancement.

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Article information

DOI: https://doi.org/10.1039/B820738K
Article type: Communication
Submitted: 19 Nov 2008
Accepted: 24 Dec 2008
First published: 27 Jan 2009

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Chem. Commun., 2009, 1508-1510

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TiO₂-assisted silver enhanced biosensor for kinase activity profiling

J. Ji, H. Yang, Y. Liu, H. Chen, J. Kong and B. Liu, Chem. Commun., 2009, 1508 DOI: 10.1039/B820738K

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