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Issue 10, 2009
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Detection of single-nucleotide mismatches using scanning electrochemical microscopy

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Abstract

Probing ds-DNA films in the presence of Zn2+ ions by scanning electrochemical microscopy (SECM) allows the unequivocal detection of a single-nucleotide mismatch and provides information about its position within the duplex.

Graphical abstract: Detection of single-nucleotide mismatches using scanning electrochemical microscopy

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Supplementary files

Article information


Submitted
06 Nov 2008
Accepted
03 Dec 2008
First published
05 Jan 2009

Chem. Commun., 2009, 1189-1191
Article type
Communication

Detection of single-nucleotide mismatches using scanning electrochemical microscopy

P. M. Diakowski and H. Kraatz, Chem. Commun., 2009, 1189
DOI: 10.1039/B819876D

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