Issue 12, 2009
From the journal:

Chemical Communications

Zn(ii) complex for selective and rapid scission of protein backbone†

Morio Yashiro,*a   Yukiko Kawakami,b   Jun-ichi Taya,b   Suguru Araib  and  Yuki Fujii*b  

* Corresponding authors

a Department of Nanochemistry, Faculty of Engineering, Tokyo Polytechnic University, Iiyama, 1583, Atsugi, Japan
E-mail: yashiro@nano.t-kougei.ac.jp
Fax: (+81)46-242-9554
Tel: (+81)46-242-9554

b Department of Material and Biological Science, Faculty of Science, Ibaraki University, Bunkyo 2-1-1, Mito, Japan
E-mail: yuki@mx.ibaraki.ac.jp
Fax: (+81)29-228-8403

Abstract

A ZnII complex with an aldehyde group hydrolyzed porcine pancreatic elastase under mild conditions, pH 8.0, 50 °C, by the Schiff base formation between the ZnII complex and the NH2 group in the protein, suggesting that a ZnII compound can be active toward peptide hydrolysis when it strongly binds to the substrate.

Graphical abstract: Zn(ii) complex for selective and rapid scission of protein backbone

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B818022A
Article type
Communication
Submitted
14 Oct 2008
Accepted
19 Dec 2008
First published
29 Jan 2009

Chem. Commun., 2009, 1544-1546

Permissions

Request permissions

Zn(II) complex for selective and rapid scission of protein backbone

M. Yashiro, Y. Kawakami, J. Taya, S. Arai and Y. Fujii, Chem. Commun., 2009, 1544 DOI: 10.1039/B818022A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements