Issue 2, 2009
From the journal:

Chemical Communications

A new quinoline sensitizer-centered lanthanide chelate and its use for protein labling on Ni-NTA beads for TRLRET assays†

Sung Hoon Kim,a   Pinghua Gea  and  John A. Katzenellenbogen*a  

* Corresponding authors

a Department of Chemistry of University of Illinois, 600 South Mathews Avenue, Urbana, USA
E-mail: jkatzene@uiuc.edu
Fax: +1-217-333-7325
Tel: +1-217-333-6310

Abstract

A quinoline sensitizer-centered lanthanide chelate system of novel design for TR-LRET was prepared; it exhibited high labelling efficiency with a his-tagged protein (ERα-LBD) on the Ni-NTA beads, using a mixed metal chelate protocol, and it functioned well in TR-LRET protein–protein interaction assays.

Graphical abstract: A new quinoline sensitizer-centered lanthanide chelate and its use for protein labling on Ni-NTA beads for TR LRET assays

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Article information

DOI
https://doi.org/10.1039/B814980A
Article type
Communication
Submitted
28 Aug 2008
Accepted
28 Oct 2008
First published
18 Nov 2008

Chem. Commun., 2009, 183-185

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A new quinoline sensitizer-centered lanthanide chelate and its use for protein labling on Ni-NTA beads for TR LRET assays

S. H. Kim, P. Ge and J. A. Katzenellenbogen, Chem. Commun., 2009, 183 DOI: 10.1039/B814980A

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