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Issue 9, 2009
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A ratiometric fluorescent sensor with a large Stokes shift for imaging zinc ions in living cells

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Abstract

The ratiometric fluorescent sensor FQ1 based on furoquinoline has been designed and synthesized, and not only exhibits a large Stokes shift of 199 nm in a mixture of C2H5OH–H2O (v/v = 8 : 2, 10 mM Tris-HCl, pH = 7.3), but can selectively detect zinc ions in the presence of competing metal ions with a red-shift of 75 nm; moreover, cell stain experiments show that FQ1 can readily reveal a change in intracellular Zn2+.

Graphical abstract: A ratiometric fluorescent sensor with a large Stokes shift for imaging zinc ions in living cells

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Supplementary files

Article information


Submitted
20 Aug 2008
Accepted
18 Nov 2008
First published
24 Dec 2008

Chem. Commun., 2009, 1061-1063
Article type
Communication

A ratiometric fluorescent sensor with a large Stokes shift for imaging zinc ions in living cells

L. Xue, C. Liu and H. Jiang, Chem. Commun., 2009, 1061
DOI: 10.1039/B814501F

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