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Issue 44, 2007
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Activity-based fluorescent reporters for monoamine oxidases in living cells

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Abstract

Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/β-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.

Graphical abstract: Activity-based fluorescent reporters for monoamine oxidases in living cells

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Article information


Submitted
28 Aug 2007
Accepted
26 Sep 2007
First published
09 Oct 2007

Chem. Commun., 2007, 4647-4649
Article type
Communication

Activity-based fluorescent reporters for monoamine oxidases in living cells

A. E. Albers, K. A. Rawls and C. J. Chang, Chem. Commun., 2007, 4647
DOI: 10.1039/B713190A

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