Issue 22, 2007
From the journal:

Chemical Communications

Site-selective depurination by a periodate-dependent deoxyribozyme†

Claudia Höbartner,a   P. I. Pradeepkumara  and  Scott K. Silverman*a  

* Corresponding authors

a Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
E-mail: scott@scs.uiuc.edu
Fax: 217 244 8024
Tel: 217 244 4489

Abstract

A deoxyribozyme is identified that mediates the site-selective depurination of its 5′-terminal guanosine nucleotide using periodate (IO4–) as an obligatory cofactor.

Graphical abstract: Site-selective depurination by a periodate-dependent deoxyribozyme

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Article information

DOI
https://doi.org/10.1039/B704507G
Article type
Communication
Submitted
26 Mar 2007
Accepted
03 May 2007
First published
10 May 2007

Chem. Commun., 2007, 2255-2257

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Site-selective depurination by a periodate-dependent deoxyribozyme

C. Höbartner, P. I. Pradeepkumar and S. K. Silverman, Chem. Commun., 2007, 2255 DOI: 10.1039/B704507G

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